Mother, children missing around Melbourne

Police and family are concerned for the welfare of a mother and her two children who were last seen in Melbourne's northeast on Saturday.

Police have appealed for public help to find a mother and her two children who are missing from the Victorian home.

Holly Mancell, 31, and her children Chloe Mancell, 12, and 6-year-old Liam Rusbridge were last seen at their home in Coldstream, in Melbourne's northeast, about 10am on Saturday.

Police and family are concerned for their welfare as Ms Mancell has a medical condition that requires medication.

It's believed they may be in the Yarra Ranges, Ringwood or Bayside areas.

Anyone who sees them is urged to contact Lilydale Police Station on 9739 2300.