The Spain international returned to the pitch in the 78th minute, shortly before Cristiano Ronaldo struck the winning goal in a 2-1 win for Zinedine Zidane's side.
The French coach started laughing when he was asked about the incident in the post-match news conference and said "he went for a shit."
Ramos poked fun at himself after the game on social media, tweeting "nature calls" along with a picture of him and Ronaldo celebrating the goal.
(Reporting by Richard Martin; Editing by Christian Radnedge)
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