Pazzini picked up the injury in Milan's Cup victory over Spezia on Wednesday.
"Pazzini suffered an injury to the deep adductor muscle in his right leg. Within 8-10 days further tests will be carried out to better understand the prognosis," the club said in a statement on Friday.
Pazzini scored his first goal since April in Milan's 3-1 win against Spezia after coming back from a long term knee injury last month.
Former Milan midfielder Seedorf takes with the ailing giants in 11th place, 10 points away from the European places, after a disastrous first half of the season in which they won only five of 19 leagues games - form that cost Massimiliano Allegri his job.
(Reporting by Terry Daley; editing by Justin Palmer)
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