"He's not quite ready yet," PSG coach Laurent Blanc told a news conference on Saturday when asked about Lucas, who has been out of action for seven weeks with a groin injury.
Although he otherwise has a full squad at his disposal, Blanc believes all his player will not be at their best after being on international duty last week.
"Having a 'clasico' after an international week is not the best idea," the former France coach said.
"The Argentine players arrived on Thursday at 6 am, jet-lagged. The preparation of the 'clasico' deserved better."
PSG lead the standings with 59 points from 30 games, two ahead of third-placed OM.
Olympique Lyonnais, second on 58, will take the lead on Saturday if they win at En Avant Guingamp (1500 GMT).
(Reporting by Julien Pretot; Editing by Ed Osmond)
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