Russian Sports Minister Vitaly Mutko wants all retested doping samples from the 2008 and 2012 Olympics to be thrown out because of alleged flaws in the reanalysis process.
"A laboratory which falsely declared a positive test result must be stripped of its accreditation and all the samples it tested must be declared invalid," Mutko told Russia's Tass news agency on Wednesday.
The IOC has reported 55 positive findings in retesting of stored samples from the 2008 Beijing Games and 2012 London Olympics.
The Russian Olympic Committee says 22 of the cases involved Russian athletes, including medallists.
Russian officials said two of the athletes were cleared when their "B" samples tested negative, contradicting the positive "A" samples.
Mutko said those two cases were enough justification for the entire retesting program to be scrapped.
Russian state sports channel Match TV previously reported that 10 Russian medallists had tested positive in retests from Beijing alone.
Also on Wednesday, a spokesman for Russian President Vladimir Putin strongly denied allegations that Mutko might be personally involved in covering up doping cases.
A documentary by German broadcaster ARD, which was broadcast on Wednesday, alleged it has evidence that Mutko intervened to bury an unnamed soccer player's positive test.
The ARD documentary also said it was told by an athlete that the disgraced coach of Russia's walkers, Viktor Chegin, who has been banned for life, was seen directing athletes secretly in Adler, near Sochi. Mutko, in an interview filmed in April, insisted that Chegin was not involved in sports.
Putin spokesman Dmitry Peskov said Russia is committed to working with international bodies to battle doping but added that "until there is hard evidence to back up those claims (against Mutko) ... we will treat this as libel."
