At least seven firefighters have been injured while battling an out-of-control blaze at Sampson Flat in South Australia's Mount Lofty Ranges.
The out-of-control bushfire is burning freely in all directions.
"One of our appliances was caught by the fire and several people have some injuries as a result of that," CFS spokesman Rob Sandford told ABC radio.
The scrub fire, near One Tree Hill, Humbug Scrub, Millbrook Reservoir, Kersbrook, Gumeracha, Birdwood and Mount Crawford Forrest, is threatening lives and homes.
The Country Fire Service says lives are at risk in towns including Upper Hermitage, Chain of Ponds, the Warren and Cromer areas and the townships of Inglewood, Houghton, Cudlee Creek, Lower Hermitage, Forreston, Lobethal, Mount Torrens, Charleston, Williamstown, Woodside, Lenswood and Mt Pleasant.
Residents should only leave if there's a clear path to a safe place.
Mr Sandford earlier said it was likely that dozens of homes had been destroyed in the blaze.
Relief centres have been opened at Golden Grove Recreation Centre and at Curdatta Cricket Club in Sandy Creek.
