Sierra Leone's Vice President Sam Sumana has placed himself in quarantine following the Ebola death of one of his guards.
The country has reintroduced travel restrictions as the number of new cases rises again.
Sumana "has decided to place himself in precautionary quarantine awaiting the results of tests by the health authorities", a spokesman said.
Sumana's bodyguard, 42-year-old John Koroma, died from Ebola on Friday, medical sources said.
Sources at the vice president's office said Sumana was not in danger but had decided to stay out of his office for the next 21 days and work from his home in the west of the capital.
The government voiced "grave concern" that the fall in the number of new cases seen in the west African nation in recent weeks has been reversed.
Ebola restrictions were eased in January as the number of new cases fell, in an attempt to boost the economy.
However, on Wednesday, Sierra Leone said it was seeing a spike in Ebola infections, blaming unsafe burials that threaten to undermine the recovery from the deadly epidemic.
The west African nation, which has registered some 3400 deaths in the nine months since the outbreak spread from neighbouring Guinea, had seen a steady decline in new cases over recent months.
Ebola, one of the deadliest viruses known to man, is spread only through direct contact with the bodily fluids of the recently deceased or an infected person showing symptoms such as fever or vomiting.
More than 9500 people have died of the disease since the west African epidemic emerged in southern Guinea in December 2013.
