Smoking costs the global economy more than $US1 trillion ($A1.4 trillion) a year, and will kill one third more people by 2030 than it does now, according to a study by the World Health Organisation and the US National Cancer Institute.
That cost far outweighs global revenues from tobacco taxes, which the WHO estimated at about $US269 billion ($A365 billion) in 2013-2014.
"The number of tobacco-related deaths is projected to increase from about six million deaths annually to about eight million annually by 2030, with more than 80 per cent of these occurring in LMICs (low- and middle-income countries)," the study said.
Around 80 per cent of smokers live in such countries, and although smoking prevalence was falling among the global population, the total number of smokers worldwide is rising, it said.
Health experts say tobacco use is the single biggest preventable cause of death globally.
"It is responsible for... likely over $US1 trillion in health care costs and lost productivity each year," said the study, peer-reviewed by more than 70 scientific experts.
The economic costs are expected to continue to rise, and although governments have the tools to reduce tobacco use and associated deaths, most have fallen far short of using those tools effectively, said the 688-page report.
"Government fears that tobacco control will have an adverse economic impact are not justified by the evidence. The science is clear; the time for action is now."
Cheap and effective policies included hiking tobacco taxes and prices, comprehensive smoke-free policies, complete bans on tobacco company marketing, and prominent pictorial warning labels.
Tobacco taxes could also be used to fund more expensive interventions such as anti-tobacco mass media campaigns and support for cessation services and treatments, it said.
Governments spent less than $US1 billion on tobacco control in 2013-2014, according to a WHO estimate.
Tobacco regulation meanwhile is reaching a crunch point because of a trade dispute brought by Cuba, Indonesia, Honduras and Dominican Republic against Australia's stringent "plain packaging" laws, which enforce standardised designs on tobacco products and ban distinctive logos and colourful branding.
The World Trade Organisation is expected to rule on the complaint this year. Australia's policy is being closely watched by other countries that are considering similar policies, including Norway, Slovenia, Canada, Singapore, Belgium and South Africa, the study said.
