Former Tottenham manager Juande Ramos will be reunited with the English Premier League side in the last 32 of the Europa League on Thursday as Spurs travel to Ukraine for their first-leg tie against Dnipro.
Ramos guided Tottenham to the League Cup title in 2008, the last time the London club won any silverware, but was unceremoniously sacked the following season.
The Spaniard, a two-time UEFA Cup winner during his reign at Sevilla, acknowledges he faces an uphill climb if he is to repeat such success with Dnipro.
"Spurs are superior. They're clear favourites and there's a very good chance of us getting knocked out," Ramos told The Guardian.
Spurs are competing for a top-four spot in the league, and despite having to travel to Norwich just three days after a 3,000-mile round trip to eastern Europe, manager Tim Sherwood insists he will field a strong side against Dnipro.
"We are out of all the other competitions and we have got a big enough squad," said the Spurs boss, who could also welcome back Brazilian midfielder Sandro after two months out.
Swansea City resume their European adventure with the visit of Serie A heavyweights Napoli to south Wales.
Gonzalo Higuain's status is uncertain with the striker struggling with a back problem, while goalkeeper Pepe Reina is also an injury concern for Napoli boss Rafael Benitez, who steered Chelsea to the title last season.
Italian league leaders Juventus were the most notable casualty from the Champions League group stage.
Three-time winners Juve host Turkish side Trabzonspor, unbeaten in this year's competition, in the first leg in Turin, while last year's losing finalists Benfica travel to Greek outfit PAOK.
Two-time former champions Porto are at home to 1980 winners Eintracht Frankfurt, while 2009 victors Shakhtar Donetsk go to Viktoria Pilsen on Thursday with past champions Ajax, Sevilla and Valencia also in action.
