With Spanish defensive midfielder Ander Herrera, signed from Athletic Bilbao, also returning after three weeks out with an ankle injury, United are hoping to kick-start their season after picking up two points from three league games and suffering a humiliating 4-0 League Cup exit at third-tier MK Dons.
Club director Sir Bobby Charlton summed up the sense of anticipation at Old Trafford on Tuesday. "It's going to be a great adventure of how we pull ourselves back around," he told the club website.
Dutch international striker Robin van Persie added: "I can't wait to train and play with the world-class players we signed...
"That feeling, that we are going to perform well, has only got stronger after the buying of players over the last weeks - I find it very exciting."
The United side is expected also to include Argentina winger Angel Di Maria, a 59.7-million-pound British transfer record signing from Real Madrid and England left back Luke Shaw, signed from Southampton.
The impending unveiling of United's reshaped team for QPR's visit eased fears on Tuesday about the fitness of defender Phil Jones, who limped out of England's 2-0 Euro 2016 qualifying victory in Switzerland after 77 minutes on Monday evening.
Jones was due to be examined by the medical staff in Manchester on Tuesday. If ruled out, he is likely to be replaced by Rojo, in the three-man defence used in manager Van Gaal's 3-5-2 system.
The arrival of Falcao roused most excitement. Spanish midfielder Juan Mata said the goalscoring South American is "not just a player, but a fantastic striker whose ability to score is extraordinary.
"I am sure he will give a lot to our group, as a person and with his goals."
United are 14th in the Premier League with two points and without a win while QPR are 12th with one win and three points.
(Reporting by Tim Collings; Editing by Rex Gowar)
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