Stephanie Frappart, Manuela Nicolosi and Michelle O'Neill were the officials for the FIFA Women's World Cup Final in France earlier this year.
But never before has a woman officiated a men's major UEFA competition final.
That will change when the trio takes charge of the UEFA Super Cup match between Liverpool and Chelsea.
"I think there is not a lot of difference because football is the same," Frappart said.
"Only teams play differently but (it's wrong to say) as a man and a woman that we cannot referee the same game between women and men.
"So for me, it's the same because refereeing is the same so football is the same, it's the same rules, so I will do the same as in women leagues."
Frappart, 35, has been refereeing in France's Ligue 1 since April and when she took charge of the match between Amiens and Strasbourg, she was the first female to referee in the French top division.
Manuela Nicolosi, Cuneyt Cakir, Stephanie Frappart and Michelle O'Neill (AAP) Source: AAP
Frappart was previously refereeing in the second division but has been promoted to the top division's pool of referees full-time for the 2019-2020 season.
"Of course my life changed because I'm more popular now in all the world," she said.
"I was also appointed in the first league in France so I know the feeling, I know the strategy and I know also my emotions so I know how to keep it and I know also how I trained for that.
"This is not the first appointment for me."
Frappart and her assistants at the 2019 FIFA Women's World Cup Final (AAP) Source: AAP
'I hope she will inspire thousands'
UEFA insists the three women have been appointed on merit and hopes they will inspire more young women to take up refereeing.
"The reason for that is because they are good. They are good, they are prepared, they are ready, they are strong; technically, physically," former professional referee and UEFA's chief refereeing officer Roberto Rosetti said.
"A few days ago she - Stephanie - she passed the men's fitness test with the elite referees, she ran a lot.
"Mentally she's strong and this is the main reason.
"I hope that she will inspire thousands and thousands of young women referees all over the world then, of course, UEFA would be, would be very happy about that."
The trio will be joined by fourth official Cuneyt Cakir, the only male member of the team.
"They are really brave. They have courage," the experienced referee said.
"They don't hesitate to give unpopular decisions. You will see tomorrow, you will see tomorrow. Believe me."
