A stunning volley by Paul Pogba set front-runners Juventus on the way to a 3-1 win at Napoli which extended their lead to three points and Cagliari gave Gianfranco Zola his first Serie A win as coach when they beat bottom club Cesena 2-1
The 38-year-old Totti, in his 23rd season at Roma, began the fightback when he turned in Kevin Strootman's cross three minutes after the break.
Then, after brilliantly hooking home a Jose Holebas cross for his 11th goal against Roma's old rivals, Totti celebrated by jumping the advertising hoardings, grabbing a camera from one of the coaching staff and taking a selfie.
Totti's afternoon, though, was nearly ruined in the last minute by Germany veteran Miroslav Klose whose close-range shot was brilliantly saved by Roma goalkeeper Morgan De Sanctis.
Stefano Mauri had volleyed third-placed Lazio in front in the 25th minute and Felipe Anderson, who set up the first goal, increased their lead with a low shot from outside the area which went through a forest of legs.
Pogba put Juve ahead after 29 minutes when he met a deflected effort with a curling volley from just inside the area.
Miguel Britos turned in a corner to equalise in the 64th minute but Martin Caceres headed Juve back in front five minutes later and Arturo Vidal fired a third in stoppage time as he finished a counter-attack in style.
Juventus have 43 points from 18 games followed by Roma (40), Lazio (31) and Napoli and Sampdoria (30).
Inter Milan, stuck in ninth place, beat Genoa 3-1 to give coach Roberto Mancini his first home Serie A win since rejoining the club in November.
Fiorentina beat Palermo 4-3 in a thrilling contest while a spectacular second-half goal from Eder, who scored with a dipping right-foot shot, gave Sampdoria a 1-0 win over Empoli.
(Writing by Brian Homewood in Berne; Editing by Ian Chadband and Pritha Sarkar)
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