Tasmanians are being urged to look out for meningococcal symptoms after five people contracted the disease in less than a fortnight, including a teenage girl who tragically died.
The state's health department on Wednesday confirmed two new cases of the disease.
The men - one aged 36 and the other in his 70s - are in a stable condition at the Royal Hobart Hospital.
A 16-year-old girl died earlier this month after contracting the W strain of the disease.
A three-month-old boy is recovering in hospital, while a 20-year-old man struck down with the B strain of the disease last week has recovered.
Preliminary testing indicates the two men have the W strain but authorities believe none of the state's five cases are linked.
"People should remain vigilant for meningococcal disease symptoms," director of public health Mark Veitch said in a statement.
"If they suspect they or someone they care for may have contracted meningococcal disease, they should seek emergency medical care immediately."
Symptoms of the disease can include fever, severe muscle aches and pains, headaches, feeling unusually unwell and confusion or drowsiness.
Late in the illness a rash can occur.
The Tasmanian government on Tuesday pledged to expand the state's vaccination program but won't release details until next week.
Free vaccinations for common meningococcal strains A, C, W and Y are available for infants in Tasmania as part of a national program.
The state government offers free vaccinations to teenagers for the W strain.
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