UEFA on Friday ordered CSKA Moscow to play their next three European home games behind closed doors and slapped them with a fine of E200,000 ($A300,000) for the racist behaviour of their supporters.
The Russian champions were also banned from selling tickets to their supporters for their next Champions League away game, at Manchester City on November 5.
The punishments follow incidents at CSKA's 5-1 Champions League Group E defeat to Roma in Italy on September 17, when a number of arrests of their fans were made inside and outside the Stadio Olimpico.
The match was also held up for two minutes after fans clashed with riot police.
"The fight against racism is a high priority for UEFA," read a statement from European football's governing body.
"The European governing body has a zero-tolerance policy towards racism and discrimination on the field and in the stands. All forms of racist behaviour are considered serious offences against the disciplinary regulations and are punished with the most severe sanctions.
"Following the entry into force of new disciplinary regulations in June 2013, the fight against racist conduct has been stepped up a level - resulting in stricter penalties to deter any such behaviour."
CSKA will therefore host Manchester City on October 21 and Roma on November 25 behind closed doors at the Arena Khimki.
CSKA spokesman Sergei Aksenov told press: "The club hasn't yet determined whether to appeal against this decision."
They already played behind closed doors in Tuesday's 1-0 home defeat to Bayern Munich as a punishment carried over from last season.
Last season, UEFA ordered the partial closure of their home venue following racist chants aimed at City's Yaya Toure during a Champions League group game between the clubs.
UEFA later ordered the fan ban to apply to the whole stadium after a further offence in the match between CSKA and Czech outfit Viktoria Pilsen.
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