Britain on Sunday reported 170 more coronavirus deaths - its lowest number since late March, when lockdown restrictions were introduced, although the figures from Northern Ireland were not included.
Prime Minister Boris Johnson meanwhile acknowledged public frustration with the restrictions imposed to fight the virus.
The deaths take the government's official rolling tally of fatalities, which includes all positive cases after tests, to 34,636 - the second-highest in the world.
Broader official data, which includes suspected deaths, is more than 36,000, although ministers say the country has passed the peak and there is a downward trend in cases.
Reporting is typically lower at weekends and business secretary Alok Sharma said technical problems meant Northern Ireland had not been included in the latest figures.
Mr Sharma meanwhile announced tens of millions of pounds in extra funding to develop a coronavirus vaccine, which could see 30 million doses available in Britain by September.
An additional $158 million would be made available to "accelerate" efforts to trial and mass-produce a COVID-19 vaccine, he said.
Vaccine 'frontrunners'
Unveiling the new funding commitments at the daily Downing Street briefing, Mr Sharma said Britain was home to two of the world's "frontrunners to develop a vaccine".
The projects, at Oxford University and Imperial College London, have already received $88 million in state aid, said Mr Sharma.
Both were making "good progress" at "unprecedented speed", he added.
Participants in the first clinical trials of the Oxford vaccine received their doses earlier this week. Imperial was set to start its tests in June and again in October.
Oxford had finalised a global licensing agreement with global pharmaceutical firm AstraZeneca for the commercial manufacturing of its vaccine, Mr Sharma said.
"This means that if the vaccine is successful, AstraZeneca will work to make 30 million doses available by September for the UK as part of the agreement to deliver 100 million doses in total," he added.
"The UK will be first to get access," he added, noting it would also work to ensure the vaccine could be made available "to developing countries at the lowest possible cost".
The business secretary also announced a $174 million funding boost to finish building a specialist "manufacturing and innovation" vaccine centre, a year ahead of schedule.
Under construction in Oxfordshire, south-central England, it is now set to open in mid-2021. It will have the capacity to produce enough vaccine doses to serve the British population within six months, the government said.
'We may never find a successful vaccine'
The new funding took government funding of vaccine development to $460 million, said Mr Sharma. But he warned "there are no certainties".
"We may never find a successful coronavirus vaccine," he added.
Prime Minister Boris Johnson, had a similar message in a Mail on Sunday article.
"We have to acknowledge we may need to live with this virus for some time to come".
He acknowledged public difficulties in adapting to the social distancing measures still in place, after the partial lifting of the lockdown in England.
"I understand that people will feel frustrated with some of the new rules," he wrote.
"I recognise what we are now asking is more complex than simply staying at home - but this is a complex problem and we need to trust in the good sense of the British people."
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