The pair, who have been sidelined since picking up injuries in the Premier League defeat at Stoke City on February 1, have not travelled to Greece.
Jones suffered concussion in a collision with Stoke's Jonathan Walters while Evans picked up a hamstring strain.
"Jones and Evans haven't travelled. Everybody else is here," Moyes told a news conference ahead of the match against the Greek Super League leaders at the Karaiskakis Stadium.
"It's a really tough game, Olympiakos have a good record here and we know, over the tie, we'll have to play well to qualify.
"Olympiakos did very well against PSG (Paris St Germain) and Benfica. They came through a difficult group, they have a great home record here. We know it will be a difficult night. They have a big support. It's far from an easy match."
(Editing by Ken Ferris)
