Victorian authorities have advised vulnerable groups including the elderly, young children, pregnant woman and people with heart or lung problems to relocate.
Authorities say the advice is precautionary but these groups should be thinking about temporarily relocating.
Health officials have stressed this is not an evacuation order but a call to temporarily relocate.
The coal mine fire expected to continue to blanket the town in thick smoke and ash for at least another 10 days.
"The smoke is very upsetting and distressing for everyone," Chief Health Officer Rosemary said.
"We do know that some groups are at higher risks than others."
Thick smoke from a coalmine fire has blanketed the town for three weeks and there are concerns for the impact the ash and smoke is having on residents health.
The Hazelwood blaze began after three fires were deliberately lit along the Strzelecki Highway near Morwell on February 9, which then spotted into a worked-out area of the mine.
Authorities stress it remains safe to stay in the area, but residents should limit their exposure.
A community respite centre has been set up in Moe and the health assessment centre has been expanded. Victorian health authorites say more than 500 people have visited the centre.
Victoria's health department is struggling to come up with some clear guidelines on the impact of the thick smoke.
