Wales could make further injury-enforced changes to their World Cup squad ahead of next Thursday's key Millennium Stadium appointment with Fiji.
Centre Scott Williams (knee) and wing Hallam Amos (shoulder) are the latest majors concerns stemming out of their 28-25 upset of England, while fullback Liam Williams was also knocked concussed from some friendly fire.
Updates on all three players could arrive on Monday, but it is thought that Scott Williams and Amos are already in doubt for the remainder of the tournament, compounding the loss of Leigh Halfpenny, Rhys Webb and Cory Allen who have already been ruled out.
Wales assistant coach Shaun Edwards said: "Hallam Amos and Scott Williams are definitely the biggest concerns, long-term. They are the ones who are the biggest concerns.
"But I think the resilience shown by these players means that if we have another player or two out of the World Cup, it just means someone else will step up and perform like we did last night."
If worst fears are confirmed with Williams and Amos, it could mean calls for the likes of James Hook, Gareth Anscombe or Tom Prydie, but Wales have little time to lick their wounds, with Fiji next up.
"We would probably look first at the original (training) squad, but we are in a situation now where we might have to spread our wings even further," Edwards added.
"Everybody is in our thoughts because we have had an incredibly bad run of luck with injuries."
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