WHO says the most vulnerable may need annual COVID-19 jabs

A document has revealed that the World Health Organization considers annual boosters for high-risk individuals as its 'indicative' baseline scenario, and boosters every two years.

Vaccine makers Moderna Inc and Pfizer Inc, with its German partner BioNTech, have been vocal in their view that the world will soon need booster shots.

A document has revealed that the WHO considers annual boosters for high-risk individuals as its "indicative" baseline scenario, and boosters every two years. Source: AP/Sipa USA Prentice C. James/Cal Sport Media

The World Health Organization (WHO) forecasts those who are the most vulnerable to COVID-19, such as the elderly, will need to get an annual vaccine booster to be protected against variants, an internal document shows.

The estimate is included in a report, which is to be discussed on Thursday at a board meeting of Gavi, a vaccine alliance that co-leads the WHO's COVID-19 vaccine programme COVAX. The forecast is subject to changes and is also paired with two other less likely scenarios.

Vaccine makers Moderna Inc and Pfizer Inc, with its German partner BioNTech, have been vocal in their view that the world will soon need booster shots to maintain high levels of immunity, but the evidence for this is still unclear.
Vaccine makers Moderna Inc and Pfizer Inc, with its German partner BioNTech, have been vocal in their view that the world will soon need booster shots.
Vaccine makers Moderna Inc and Pfizer Inc, with its German partner BioNTech, have been vocal in their view that the world will soon need booster shots. Source: AAP
The document shows that the WHO considers annual boosters for high-risk individuals as its "indicative" baseline scenario, and boosters every two years for the general population.

It does not say how these conclusions were reached, but shows that under the base scenario new variants would continue to emerge and vaccines would be regularly updated to meet these threats.

The UN agency declined to comment on the content of the internal document.

A spokesperson for Gavi said COVAX was planning to take a wide range of scenarios into consideration.

The document, which is dated June 8 and is still a "work in progress" also predicts under the base case that 12 billion COVID-19 vaccine doses will be produced globally next year.
That would be slightly higher than the forecast of 11 billion doses for this year cited by the International Federation of Pharmaceutical Manufacturers & Associations (IFPMA), signalling that the UN agency does not expect a significant ramp-up of vaccine production in 2022.

The document predicts manufacturing problems, regulatory approval issues and "transition away from some technology platforms" as potential drags on supplies next year.

It does not signal which technologies could be phased out, but the European Union, which has reserved the world's largest volume of COVID-19 vaccines, has bet heavily on shots using messenger RNA (mRNA) technology, such as those by Pfizer and Moderna, and has forgone some purchases of viral vector vaccines from AstraZeneca Plc and Johnson & Johnson.

Worst case scenario

The scenarios will be used to define the WHO's global vaccination strategy and the forecasts may change as new data emerges on the role of boosters and the duration of vaccine protection, Gavi says in another document, also seen by Reuters.

So far about 2.5 billion doses have been administered worldwide, mostly in rich countries where over half of the population has received at least one dose, whereas in many poorer countries less than 1 per cent has been vaccinated, according to Gavi's estimates.

This gap could widen next year under the WHO's most pessimistic forecast, as the need for annual boosters could once again push poorer nations to the back of the queue.
In its worst-case scenario, the UN agency says production would be 6 billion doses next year, due to stringent regulation for new shots and manufacturing issues with existing ones.

That could be compounded by the need for annual boosters for the entire world, and not just the most vulnerable, to combat variants and limited duration of protection.

In the more optimistic situation, all vaccines in the pipeline would get authorised and production capacity would ramp up to about 16 billion doses to meet demand. Vaccines would also be shared equitably across the world.

There would be no need for boosters as vaccines would show strong efficacy against variants and long protection.


Share
4 min read

Published

Updated

Source: Reuters, SBS


Share this with family and friends


Get SBS News daily and direct to your Inbox

Sign up now for the latest news from Australia and around the world direct to your inbox.

By subscribing, you agree to SBS’s terms of service and privacy policy including receiving email updates from SBS.

Download our apps
SBS News
SBS Audio
SBS On Demand

Listen to our podcasts
An overview of the day's top stories from SBS News
Interviews and feature reports from SBS News
Your daily ten minute finance and business news wrap with SBS Finance Editor Ricardo Gonçalves.
A daily five minute news wrap for English learners and people with disability
Get the latest with our News podcasts on your favourite podcast apps.

Watch on SBS
SBS World News

SBS World News

Take a global view with Australia's most comprehensive world news service
Watch the latest news videos from Australia and across the world
WHO says the most vulnerable may need annual COVID-19 jabs | SBS News