In February, the 57-year-old took over from former Zamalek and Tottenham striker Ahmed 'Mido' Hossam - who lasted just 37 days in the job and found out he had been dismissed from a live television interview with the club's chairman.
Mohamed Helmy has taken over as interim manager, with the board set to name a successor in the coming days.
Second-placed Zamalek, who trail Al Ahly by 11 points, are due to visit second-to-last Ghazl El Mahalla on Saturday.
(Reporting by Shravanth Vijayakumar in Bengaluru; Editing by Hugh Lawson)
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