Former world No.2 Vera Zvonareva has returned from a 17-month hiatus, falling to Chinese star Li Na at the Shenzhen Open.
The 31-year-old Li, Asia's highest-ranked player in tennis history, beat Zvonareva 7-5 6-3 in one hour and 46 minutes.
It was the first singles event for Zvonareva since the 2012 London Olympics, after which the 29-year-old was sidelined due to illness and a shoulder injury.
Zvonareva had triumphed over Li in four of their previous five meetings, the most recent of which came in 2010.
Taiwan's Chan Yung-Jan, meanwhile, scored a surprise victory over sixth-seed Zhang Shuai of China.
Chan won 3-6 6-4 6-2.
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