Hundreds of people are expected to gather near the remote Innamincka township for an historic native title determination on Wednesday.
The Yandruwandha Yawarrawarrka people will be formally recognised as the traditional owners of a 40,000 square kilometre area of far north eastern South Australia during a special bush hearing of the Federal Court.
The claim covers an area stretching along the northeastern corner of the state to the Queensland border and includes seven pastoral leases, conservation areas, Innamincka and the eastern edge of the oil and gas hub of Moomba.
It also covers several historically significant sites used by Burke and Wills with whom the Yandruwandha Yawarrawarrka people share history.
The Aboriginal group provided food and shelter to members of the ill-fated explorer party, 150 years ago.
The determination will protect the Yandruwandha Yawarrawarrka people's rights and cultural heritage interests, including rights to camp, fish, hunt, collect natural resources and maintain cultural practices.
Wednesday's hearing will take place at Cullyamurra Waterhole, 15 kilometres from the outback tourist hotspot of Innamincka.
It comes after nearly 100 community representatives agreed to resolve the case without a trial during a meeting in Adelaide in October.